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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c4fa8a5819a8ff8d0cd8fe2c2afc3f02591961c3e21ed480c0d83dc16bf985' 
  AND token = 'A5qT99sG0owwHXuEem2/fgtY6b24z4Yk1uuudqYIvuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}