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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d57309fae977398f278696eb157a3f8ae99093d252b3cbd4317545afe96c362' 
  AND token = 'SHhuSIkSVtcJdsj7JTg1m+pnjWgCUSYTySfe09w1RC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}