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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82043435268ad01481d9fd36432a0206dc1a660c23043b64b100645b9099b13f' 
  AND token = 'C40JCS7S5/1WP4cUyR2TcFwmpinnvMEUUtKawikWLgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}