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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f494a6426dbff1e31691949ab3168763d2a48d42617a0b7d9e305c947adccc51' 
  AND token = 'uJD6VHlu/BUcSUoEilrBHQM3t8IYUC0Doz52bsjFTAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}