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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bbb646e09fc46e2680818c5c3c86bf5de6b89a18bc90937f157adf83b789f80' 
  AND token = 'yy5GIr5kWw8/1nEpRNDlylAQ8feRiFD/aXx1RS0RRKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}