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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3e0b00e9a331dcd0b2aaa43b87984573e449d4ae7aee43085d49472cb7e822' 
  AND token = '+BhYnWsosHAQAlz6NIvAW9C08MAIWJGO5vvyfl7vPJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}