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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0d357e22cc7f76c784dc20e279db2b2fd6aadbc33200e68210f334d7c3e5d12' 
  AND token = '1s2hKuGvBrN4zaw/pk7Z3hpzoQZJVR/1F/qSWR2dksI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}