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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd6b90d5c8d7003619906d4b26ba0a2fddbf4558cdcef00a6645cf2df5d2757' 
  AND token = 'PFHhUCeAslpp75DmXjNMAcO3cG6P5qx29uAIWZGU26Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}