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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8925c9e78685c0d51d925280cc7810aa2870d7fb567e548ae9e3c6c86815fcd0' 
  AND token = 'DrT1uF7fz4W3l/Lj4ytl+dNpbKqT58qklNVmkK9bRgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}