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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d58a7ea546a2eece59fddc9a2cdcadb33eddd8abb4963323356a6078e06271' 
  AND token = '/4kc9jWmexe+O4cGL04n4TZxRPMxQj7C0nYurkCiyM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}