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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4ea202d4bec77f6402a200cd70b26184b51383bfc68e6f9293811e4bff687d' 
  AND token = 'JZkkoXDRN2/K9xqTkGjnw+9xS6ay/aLXbTL7tY3Ojgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}