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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577aa59d3350f884cf77bfd40ed5a2c7e400449548f953ab48fa52e805be9904' 
  AND token = 'ZbNIznwtHpmU9TyjTsGQudXoh0/hgoJ53Y+60RZPA0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}