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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea176b0971a108d5de43c782c3e9034e611339fa13f36c3e4892fc9906b5109' 
  AND token = '3lfAtmKqUgAj2st/y6e1L2aT0ekFCQMeliTe0bnczNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}