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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b9ec5d4a7fcb7875a7d6871eaff9d034b565e208c565e52c5f7b8162f804788' 
  AND token = 'ma8iieUwVK6Lfz3zZbu2az8kjQeObiwwOGMrH7OvZiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}