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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6269b82fba2b8494fdd1351b23ebc79f4bbb7714def4b12ea7bfc143ee58b5f' 
  AND token = 'Hegw+tMi2ydt9Xcu3fy9xHsNW2rr6ud5v4DsvdewVZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}