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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fbb897138e8081c1637fdda9f69e6d8ab50cf18ff941a5d8937e589a2e74410' 
  AND token = 'DEZNGvBGcHE+SR77JvoAD2ueXAdSSTZ73lt2uE2HcOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}