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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e253c47a949d1ad4282f2e48df8a8fb824976b8f45530afa46e20de613dc7b9' 
  AND token = 'YHVbWnyBeP9UYrLIfq8mVsobRq4xpcSg9dNdF0Ia25g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}