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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7168eadfd1a713c5a305eb09d82fb427c0fa6af8df7557750b367bdc2878c1f6' 
  AND token = 'OYSy7CWyQR5sSy0fFyh13j3aXsF8Rynf8oibvCiBCgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}