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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41cd40070b214c454b672e99f4d795a790059827e1c97b219c730650043ce076' 
  AND token = '4TcSLgtjrC/MWGzRIA+SyAkB+P/16R5jLFrkzaElHSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}