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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3805e3c84161e47c4097da30c13f0d4531e5d6aa0a2240e1d5818ac12e08895' 
  AND token = 'i9IYsxc2CFFKG3Fetb0lXP7iiBW4gmEQXDtDkEVzRHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}