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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dfc7bca5b89453f4dbaacb945cbaea420425d763393f96dadae79d0bf681b7a' 
  AND token = 'ygrzoZVMYaVEW0IdLm7m5TLuO5MQucMz/WBxOcK8AIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}