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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd42570e22b3308655d1074dff242272ed55c665a71e6c63202f8d42ec82b1a3' 
  AND token = 'B340EDZ4t0CiHAA9Mbhgj02cEfSuOTzrcSuetr+tvtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}