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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '906af21725158b3c477472de83975f43157aa228528855075221b8cfb5f6548d' 
  AND token = 'n0YCYE47JIZ6vxh62dofCloDphug3CY0zA3+w78zz5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}