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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8ff68ed5853613fc87ca1ca940d0a01d4ddd0430a861578e92d3c8fbcecf7f' 
  AND token = 'z+Qviu4iaTedX6vSBoUD0aKx86qModR5GyMf6O5wU9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}