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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972570a33b021f4a4d29f14ab5ee83bd14e66e32ea9fb7aa771b401880f5a29d' 
  AND token = 'IOcivTdTIITw1vFGQ3luZS44LDJ4nkVbLWUqy9rtVL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}