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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145ddc03cabfbec83fe042f2b0cd7cece4021b859fd6137a9f71e3eda2483293' 
  AND token = 'FQdUtdXetvM7tLrmib42/nTKvLz+QunomQCOK7E4GS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}