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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd608ceb6dc8776762acde8d46c244f19282372063ec7aac13798405c535e34b1' 
  AND token = 'A+IHwNMsk/i0zE0OL88dm1uR0XI+kxWpQEkV8QM9k3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}