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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f85b123113ebaf5ced260d1d4e3e98543d561458e67f8adc64c020e1a2e8c5b' 
  AND token = 'bQHcDfkyJVnAI847rN2XuncTqeaNUULSdZAwOKx8xJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}