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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ed2dccf4589d49045cf62c17cdf7af52a7597d8ed9c1730d420d770459f2e0' 
  AND token = 'SHGWYjhkBZbncPywe7lzRxKpZc5EqrcCzSxv1ld5lRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}