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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6b256def490ef378488943827e863dba4fee61fc2dcceb819fc9e7f6d591b68' 
  AND token = 'qYM2kbbmHjqx9gAuSFzrz7mI4Ezog+tHN3TJYabqa+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}