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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e291ec0b37096eca1bcb91a8114dca20c0148f3846e29c6d0d257a0b6a6c2e97' 
  AND token = 'ENQgBTxc2xm2ccwbKIXfPRa0MEYAbOdkZ1Jh5YML1pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}