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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6136a3396a2ba1657f6211cdf4c56dc080ca199772b9b31bc4107e0e42136697' 
  AND token = 'nskYGRWYP1tsPQEWx2Y0RAIjh0Ajc7FCUaxmZhx43No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}