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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cecd72b0f65afce99c417bccf2b0a7e2758beb7f8292ab9741f7e3fb397c0a83' 
  AND token = 'qKZr1HNIF8P7lylipAYBH2GkZDVQoQeJiu68qwyHdJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}