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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeb9467b94c6ad4a08b0c8d8bfd4217a43add491d65a961bade8e8816f63fba3' 
  AND token = 'qvaDhIp/LP4lkdH4fZW1kUkz4gYEM8Nj3KyvZAUyzr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}