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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bf9653dfb2c99cc3766afdf3e9012ec4d3f142189d5192f686f38a90897b08c' 
  AND token = '3MihXCyp4WIwDYnpiEcrWrsSdssiTIa0+SVIxOT0RhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}