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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0e4eee9198cdeab6f6e8e929e932b69262ea7b167ce75fc6b170a853cd42a4' 
  AND token = 'JjvGbKTRUOHi/l++NvosjLKaE1x86DRKuy0fa8Wmqgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}