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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b71fbd5bb5184c610ea28681a6336e5af1361f944376160147063ee72fbd2699' 
  AND token = 'ZIbSnYM1VsRvaylEZv2PHtOYh3Ff9MOUzS20eK4FJbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}