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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43695543d75cf0f4a4ca80619e2ce051a7ab09629c76870401a46bd51fb7625' 
  AND token = 'ed9gIMw7RlvOU77oiOSa1aWEtwyYTyzQYb1Q4y6ausA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}