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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8110b233efb192279d8bcf75acf217e4ad8c8cd5bf0f0f5b6e6d9d850ee322' 
  AND token = '0YR2w1O+9d/RoczuyhL8weGZ5+nSjP5yAjVa3WU/7uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}