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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd213b257f9221c3493fbb78861a86301a7d98c5ad98605f1785cdb3dd6eb0521' 
  AND token = '0CSxyskfJ2Gi4Nf/qPfTLZeCzxeubFMiGS+ErC9B1ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}