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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6210ca2ef8856c725cf466c2fc8efa46b6bda490fdeb2a11c3d81a2cf8c7a70d' 
  AND token = 'fWWI0Qew/CvjJBNd7+H3I8ryHx9aVmzarlb9fAt/XRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}