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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f521f49157eec24818ec0734ffd8d03c07a778c6bed3ffbb5bf22390b9d858' 
  AND token = 'rzZVk8gIYasf5M3LS65b98uJvdzA1M+rr1VGmsbyTBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}