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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee2b358bc16dc38b3fed1a91c91e1d8739cf02451d21693d29ffe41f8e8dafe9' 
  AND token = 'RFusuJElxscKfSUKLWN2NgZ0cCEe3TEipXDoKJoBh5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}