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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b43aba6184dfe5284029744ebd1e9d9064f875f3d8affe6e6a80fe042caf511' 
  AND token = 'HhDv11rhVYgxO2HiEOfKRR26wNNrxv383rJgR0As9gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}