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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45002e83f61add58e51c2c1f64eaab5d3bd510fae50a8d1160f54e9fd2724630' 
  AND token = '+YttT2AuOZtu6Iyz/PHW8ViMC7y1iVkbSHT4T5jfPo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}