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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c904c60da248ef18a864822e06cd40c6043fcfabaab930f6c540658d1f064cb' 
  AND token = 'jr3UGY3KDHA2q4/7Gbr1VydnjMLfC5EDH/xmcHjVwwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}