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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f22a9ef53266c420793efcb6c2e0166c8f375637ea62af4cedf80f3fb9d1911' 
  AND token = 'cjJBNXfbmaSZCJ0saRcQ/Is147Oe4pv/JeEaPWQyBoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}