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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61fd9c1dfbce7725b22cca451177339d5ee0bb1bcf0883ef425482cab200f082' 
  AND token = 'E9kOH4whrBSDtDITMH8KQW0cArAsu03Rj8SMRq9ocJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}