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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50aa78f5c7eab81b0bf9775697443946904bed9d914757d3b60d593912cc1bd0' 
  AND token = 'nsIvcYPh7p6Rk500NBjdnBRuUYUXxLy4xfI52XUYTDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}