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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7fe4777e089a6580d0372519514252fd01f828580b74e604bc5fb60e882b2ae' 
  AND token = 'Kss2egoCDzY53feIMNgpu1rV3DnllYYxEfz6NkMHNrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}